Literature Database Entry

torres-gomez2025programmable

Jorge Torres Gómez, Mohammad Tauqeer Alam, Markus Ralser and Falko Dressler, "Programmable Metabolic Disruption in Yeast Cells via Targeted Terahertz Excitation of Enzymes," Proceedings of 12th ACM International Conference on Nanoscale Computing and Communication (NANOCOM 2025), Poster Session, Chengdu, China, October 2025, pp. 153–154.

Abstract

Standard practices in microbiology often require genetically modifying the operation of cells. The process is quite complex and time-consuming as it involves manipulating cells at the gene level. To overcome these drawbacks, we present a conceptual design for a non-contact and non-invasive procedure utilizing terahertz waveforms. We propose equivalent methods to suppress gene expression by targeting the protein associated with the gene. Relying on techniques from the reported literature, we outline a procedure in which terahertz waveforms transfer energy to a targeted enzyme within yeast cells to unfold the enzyme. As such, the enzyme is blocked from catalyzing associated metabolic reactions, thereby making the cell deficient in a particular enzyme on demand.

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Jorge Torres Gómez
Mohammad Tauqeer Alam
Markus Ralser
Falko Dressler

BibTeX reference

@inproceedings{torres-gomez2025programmable,
    author = {Torres G{\'{o}}mez, Jorge and Alam, Mohammad Tauqeer and Ralser, Markus and Dressler, Falko},
    doi = {10.1145/3760544.3765633},
    title = {{Programmable Metabolic Disruption in Yeast Cells via Targeted Terahertz Excitation of Enzymes}},
    pages = {153--154},
    publisher = {ACM},
    address = {Chengdu, China},
    booktitle = {12th ACM International Conference on Nanoscale Computing and Communication (NANOCOM 2025), Poster Session},
    month = {10},
    year = {2025},
   }
   
   

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Last modified: 2025-11-10