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Jorge Torres Gómez, Anke Kuestner, Jennifer Simonjan, Bige Deniz Unluturk and Falko Dressler, "Nanosensor Location Estimation in the Human Circulatory System using Machine Learning," IEEE Transactions on Nanotechnology, vol. 21, pp. 663–673, October 2022.


The human body can be considered a complex natural network due to the variety of interconnections between the different body regions. One example is the network of blood vessels, where artificial communication channels can be rendered using nanosensors that travel in the bloodstream as collectors and carriers of information. Further advancing this vision, in this work we investigate the detection and localization capabilities of flowing nanosensors in the blood flow to report abnormalities in the human body. Specifically, we target the detection of quorum sensing molecules and provide a methodology to evaluate its performance. The methodology consists of modeling the traveling path of nanosensors along the vessels through a Markov chain, and the use of machine learning (ML) models to compute their transition probabilities. We illustrate the resulting distribution of nanosensors in the body, which evidences a close match to expected results. We also evaluate their detection and localization capabilities in different body regions revealing their effectiveness to determine the presence of abnormalities in the human vessels.

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Jorge Torres Gómez
Anke Kuestner
Jennifer Simonjan
Bige Deniz Unluturk
Falko Dressler

BibTeX reference

    author = {Torres G{\'{o}}mez, Jorge and Kuestner, Anke and Simonjan, Jennifer and Unluturk, Bige Deniz and Dressler, Falko},
    doi = {10.1109/TNANO.2022.3217653},
    title = {{Nanosensor Location Estimation in the Human Circulatory System using Machine Learning}},
    pages = {663--673},
    journal = {IEEE Transactions on Nanotechnology},
    issn = {1536-125X},
    publisher = {IEEE},
    month = {10},
    volume = {21},
    year = {2022},

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